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Dr. Jean-Philippe Sobczak

Jean-Philippe holds a Ph.D. in physics and is a DNA-origami designer and project manager at tilibit nanosystems. Jean-Philippe has unique knowledge about the DNA origami folding process. He is trained in real-time fluorescence analysis and electron microscopy imaging.

Dr. Klaus Wagenbauer

Klaus is a DNA origami designer and research scientist at tilibit nanosystems. Klaus is experienced in the folding of complex and functional DNA origami structures and multimer assemblies, as well as electron microscopy (negative stain and cryo) and single particle analysis and reconstruction.

Christian Sigl

Christian is a DNA-origami designer and research scientist at tilibit nanosystems. Christian is experienced in the folding of complex and functional DNA origami structures, with a focus on the assembly of artificial virus-like particles. He is trained in electron microscopy imaging (negative stain and cryo) and single particle analysis and reconstruction.

Pierre Stömmer

Pierre is a DNA-origami designer and research scientist at tilibit nanosystems. Pierre has unique expertise in the folding and purification of complex 2D and 3D DNA origami structures. He is trained in electron microscopy imaging and single particle fluorescence measurements.

Eva Bertosin

Eva is a DNA origami designer and research scientist at tilibit nanosystems. Eva is experienced in the design and folding of complex DNA origami structures, as well as single particle analysis and reconstructions by cryo electron microscopy.


 

Selected Publications

 

P. Ketterer*, A.N. Ananth*, D.S. Laman, A. Mishra, E. Bertosin, M. Ganji, J. van der Torre, P. Onck, H. Dietz, and C. Dekker, 'DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex', Nature Communications (2018), vol 9, article #902, doi 10.1038/s41467-018-03313-w

H. Franquelim, A. Khmelinskaia, J.P. Sobczak, H. Dietz, and P. Schwille, 'Membrane sculpting by curved DNA origami scaffolds', Nature Communications (2018), vol 9, article #811, doi 10.1038/s41467-018-03198-9

K. Wagenbauer, C. Sigl, and H. Dietz, 'Gigadalton-scale shape-programmable DNA assemblies', Nature (2017), vol 552, p78-83, doi: 10.1038/nature24651

J. Funke*, P. Ketterer*, C. Lieleg*, S. Schunter, P. Korber, and H. Dietz, 'Uncovering the forces between nucleosomes using DNA origami',  Science Advances, (2016), doi 10.1126/sciadv.1600974

J. Funke and H. Dietz, 'Placing molecules with Bohr radius resolution using DNA origami',  Nature Nanotechnology, (2015), doi 10.1038/nnano.2015.240

T. Gerling, K. Wagenbauer, A. Neuner, and H. Dietz 'Dynamic DNA devices and assemblies formed by shape-complementary, non-basepairing 3D components' Science, vol 347 (2015), p1446-1452

K. Wagenbauer*, C. Wachauf*, and H. Dietz 'Quantifying Quality in DNA Self-Assembly' Nature Communications, 5:3691 (2014), doi: 10.1038/ncomms4691

J. Sobczak, T. Martin, T. Gerling, and H. Dietz, 'Rapid folding of DNA into nanoscale shapes at constant temperature',  Science, vol 338 (2012), p1458